Low Dose Naltrexone Therapy

Naltrexone is an FDA-approved drug that has been used to treat alcohol and opioid dependence. At low doses, however, it is effective in treating chronic pain, and proponents of LDN suggest that it has potential benefits in reducing the symptoms of a variety of medical conditions, including autoimmune diseases (e.g., fibromyalgia, rheumatoid arthritis, lupus, and Crohn’s disease), some cancers, dissociative disorders such as personality disorder and post-traumatic stress syndrome (PTSD), central nervous system disorders (e.g., Parkinson’s disease, multiple sclerosis, and Lou Gehrig’s disease), and HIV/AIDS. There is also some evidence to show that LDN may halt the progression of some medical conditions.

For further informatin on how LDN may help your condition, contact RevitaLife and schedule a consultation to determine if LDN would be of benefit to you.

Chronic Pain

For chronic pain, LDN acts an analgesic and anti-inflammatory agent in the central nervous system when administered in a daily dose that is about one-tenth the amount used for opioid addiction. With higher doses of naltrexone, however, positive effects on pain have not been reported.

Fibromyalgia is one example of a chronic pain condition that has responded to LDN despite the fact that this condition does not respond to common anti-inflammatories and does not appear to be an inflammatory disorder in the classic sense. Symptoms associated with fibromyalgia include musculoskeletal pain, sensitivity to mechanical stimulation, extreme fatigue, cognitive disturbance, and difficulty sleeping. The theory is that LDN increases the production of endorphins, which inhibit the transmission of pain signals and produce feelings of well-being.

Man with Back and Neck Pain

Other Benefits of LDN Therapy

  • Autoimmune Diseases – Patients with autoimmune diseases have had exceptional success with LDN. The scientific community has increasingly recognized that autoimmune diseases result from immunodeficiency, which disturbs the normality of immune system. LDN helps to restore normalization of the immune system, making this drug effective in these diseases.
  • Cancer – Recent research, published in the International Journal of Oncology (June 2016), cites the anticancer activity associated with LDN due to its ability to reduce tumor growth by interfering with cell signaling and modifying the immune system. LDN treatment was deemed more effective when altering the treatment schedule rather than by continuous treatment with LDN. Patients with kidney cancer, chronic lymphocytic leukemia, multiple myeloma, and non-Hodgkins lymphoma have reported individual improvements with LDN therapy.
  • Dissociative Disorders/PTSD – LDN has been increasingly used as a medication for dissociative symptoms since 1999 when a study reported some positive and lasting effects on patients. They experienced a decline in symptoms and a clearer perception of their surroundings and improved their assessment of and ability to deal with reality. These results supported the theory that blocking opioid receptors leads to a decline in opiate-modulated dissociative phenomena.
  • Central Nervous System Disorders – The clinical use of LND has increased over the years for treatment of central nervous system disorders. LDN has been consistent in preventing attacks in MS patients and has reduced the frequency of muscle spasms and fatigue associated with MS. In patients who are actively experiencing an MS attack, rapid resolution of the attack has occurred when starting LDN.
  • HIV/AIDS – LDN has demonstrated consistent beneficial effects in treating HIV/AIDS. Many patients have used LDN alone, which improved their CD4 counts (a measure of specific white blood cells that fight infection and stratify the patient’s stage of HIV or AIDS). Some patients have used LDN in conjunction with highly active antiretroviral therapy (HAART), which further increased the effectiveness of the combination drug therapies in many of these patients.